Placental Neuropeptide Y (NPY) and NPY receptors expressions and serum NPY levels in preeclampsia
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چکیده
منابع مشابه
Galanin-neuropeptide Y (NPY) interactions in central cardiovascular control: involvement of the NPY Y receptor subtype.
The interactions between neuropeptide Y (NPY), specifically through NPY Y(1) and Y(2) receptor subtypes, and galanin [GAL(1-29)] have been analysed at the cardiovascular level. The cardiovascular effects of intracisternal coinjections of GAL(1-29) with NPY or NPY Y(1) or Y(2) agonists, as well as quantitative receptor autoradiography of the binding characteristics of NPY Y(1) and Y(2) receptor ...
متن کاملNeuropeptide Y (NPY) synthesis in lymphoblasts and increased plasma NPY in pediatric B-cell precursor leukemia.
Neuropeptide Y (NPY), a regulatory peptide in both the central and peripheral nervous systems, has recently been found in neuroendocrine tumors as well as in the bone marrow of rat and certain autoimmune mice, but not in human bone marrow. To investigate a possible role for NPY in the human hematopoietic system, we have prospectively studied NPY-like immunoreactivity in plasma (P-NPY-LI) and NP...
متن کاملRenal and Cardiac Neuropeptide Y (NPY) and NPY Receptors in a Rat Model of Congestive Heart Failure
Neuropeptide Y (NPY) is co-released with norepinephrine, and stimulates vasoconstriction, vascular and cardiomyocyte hypertrophy via Y1 receptors (R), and angiogenesis via Y2R. Although circulating NPY is elevated in heart failure, NPY’s role remains unclear. Activation of the NPY system was determined in Wistar rats with the aortocaval (AV) fistula model of high-output heart failure. Plasma NP...
متن کاملProspective evaluation of leptin and neuropeptide Y (NPY) serum levels in girls with anorexia nervosa.
OBJECTIVES The pathogenesis of anorexia nervosa (AN) remains still unclear. It has been reported that neuropeptides may play a role in the control of appetite and hormone release contributing to hormonal disturbances in AN. However the question if neuropeptide alterations are consequence or cause of malnutrition is still unresolved. METHODS Serum leptin, neuropeptide Y (NPY) concentrations as...
متن کاملNeuropeptide Y (NPY) potentiates phenylephrine-induced mitogen-activated protein kinase activation in primary cardiomyocytes via NPY Y5 receptors.
Neuropeptide Y (NPY) has been shown to participate in the cardiovascular response mediated by the sympathetic system. In this report, we investigate the growth factor properties of NPY on cardiac myocytes. Mitogen-activated protein kinases (MAPK) are key signaling molecules in the transduction of trophic signals. Therefore, the role of NPY in inducing MAPK activation was studied in mouse neonat...
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ژورنال
عنوان ژورنال: Experimental Biology and Medicine
سال: 2019
ISSN: 1535-3702,1535-3699
DOI: 10.1177/1535370219831437